Reviewing IRBs

Using irex as the reviewing irb

document reliance arrangements

Use IREx to capture site’s agreement completion and study-specific cede decisions, as well as document the flexible elements of reliance.

capture site-specific local considerations

Use IREx to centralize the collection of study-specific documentation from sites and their progress completing the steps to reliance.

facilitate communications with sites

Use IREx to automate communications with site HRPPs and study teams around reliance decisions, site progress towards reliance, and sIRB approvals.

provide tools for lead study teams and coordinating centers

Use IREx to empower your study manager (lead study team/coordinating center) to help with sIRB coordination and tracking.

resources for using IREx

Complete Your Institutional Profile

  • About your site
  • General laws & policies

Serve as the
Single IRB

Customize the Study-Specific Reliance Plan

Add Your FWA Components

  • Same legal entity
  • Location specificity

Track Letters of Indemnification (LOI)

  • Your institutional LOI
  • External LOIs executed

Study-specific Local Considerations (LC)

IREx Demo Site Now Available!


If you are curious about how to use IREx as the Reviewing or Single IRB, you can now practice in the IREx Demo site! Contact us (admin@IRBExchange.org) to request access to the IREx “Sandbox” where you can practice creating studies and using various IREx featues before setting up your study in the live site.

other tools to support your reliance process

Template Reliance Instructions

(Editable)

  • List sIRB & study contacts
  • Outline reliance process for participating sites
  • Indicate required agreements
  • Describe consent form process
  • Include site submission process

Using IREx to fulfill SMART IRB Documentation and Notification Requirements

  • Notify sites of cede decisions (SMART IRB section 3.4)
  • Notify site investigators and relying institutions of review decisions (SMART IRB section 5.9)