A freely available, web-based portal supporting single IRB review documentation and coordination for multi-center clinical trials.
What IREx Users Say
Who Uses IREx
51 institutions are using IREx as their single IRB portal to document reliance, capture local considerations, and share sIRB approval with relying sites. Join them!
IREx Agreement Checker
The Agreement Checker can be useful in gauging site readiness and preparing reliance instruction for sites. Check if participating sites on your study are ready to rely on the sIRB!
Our Metrics
As of June 30, 2026 ...
- 97% of sites in IREx have completed their Institutional Profile
- 90% of IREx sites used IREx to rely on a sIRB
- 92% of sites have made it through the sIRB process and received initial approval
- 51 single IRBs are using IREx for over 800 studies
- 13 median days from sIRB submission to sIRB approval for relying sites (not including local review time)
