Studies

IREx contains 127 multi-site studies.

Study Title Lead IRB Approved? Sponsor
A Community-based Assessment of Skin Care, Allergies, and Eczema (CASCADE) Univ of Utah Yes NIAMS
A Phase 1 Pilot Safety and Feasibility Study of Autologous Engineered Urethral Constructs for the Treatment of Strictures Wake Forest Univ Hlth Sci Yes Other
A Placebo-Controlled Effectiveness in INPH Shunting (PENS) Trial: Proof of Concept Johns Hopkins Univ SOM No Codman (DePuy)
A pragmatiC sTrategy to promote actIVity and Enhance quality of life AFTER Transcatheter Aortic Valve Replacement: ACTIVE AFTER TAVR Vanderbilt Univ Med Ctr Yes Investigator
A Prospective Comparison Study of Electronic vs Paper Feedback and Its Relationship with Clinical Outcomes at a Sports Medicine Center Tulane Univ Yes Investigator
A randomized open label trial of spironolactone versus prednisolone in corticosteroid-naive boys with DMD Nationwide Children's Yes Other
A randomized, double-blind, placebo controlled trial of testosterone undecanoate for optimizing physical and cognitive performance during military operations (OPS II) Pennington Biomed Yes DoD
A Randomized, Double-Blind, Placebo-Controlled Trial to Assess the Efficacy and Safety of Misoprostol in the Prevention of First Recurrence of Clostridium Difficile Infection in Adults Aged 50 and Over Vanderbilt Univ Med Ctr Yes NIH
Addressing Post-Intensive Care Syndrome (APICS) Vanderbilt Univ Med Ctr Yes Other
Allogeneic Bone Marrow-derived Human Mesenchymal Stromal Cells for the Treatment of Acute Respiratory Distress Syndrome After Trauma Vanderbilt Univ Med Ctr No Other
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation after CABG (CTSN PACES Trial) Vanderbilt Univ Med Ctr No Other
Apixaban for the Secondary prevention of Thromboembolism: A prospective Randomized Outcome pilot study among patients with the AntiphosPholipid Syndrome (ASTRO-APS) Univ of Utah Yes Investigator
APOLLO Wake Forest Univ Hlth Sci Yes NIDDK
Assessing Status of Diabetes Care in Louisiana Pennington Biomed Yes LaCaTS
ASSESSING THE ASSOCIATION BETWEEN OBESITY, DIABETES, METABOLIC SYNDROME AND THE RISK OF BREAST CANCER Pennington Biomed Yes LaCaTS
B-WELL - Mom (Asthma Cohort Support Contract) Univ Alabama-Birmingham Yes NICHD
Bilateral Transfer of Motor Skills and Brain Activation Patterns Pennington Biomed Yes Other
Characterizing Uveitis by Gene Expression Univ of Utah Yes NEI
CISTO: Comparison of Intravesical Therapy and Surgery as Treatment Options for Recurrent Bladder Cancer Vanderbilt Univ Med Ctr No PCORI
Comparative Effectiveness Analysis of Surgery and Radiation (CEASAR) for Localized Prostate Cancer Vanderbilt Univ Med Ctr Yes PCORI
Comparison of Oral anticoagulants for extended VEnous Thromboembolism (COVET) Vanderbilt Univ Med Ctr Yes PCORI
CPCCRN (CIRB): GM-CSF for Reversal of immunopAralysis in pediatriC sEpsis-induced MODS (GRACE) Univ of Utah Yes NICHD
CPCCRN 000: CPCCRN Core Data Project (CCDP): Characterizing Patient Populations in the Collaborative Pediatric Critical Care Research Network (CPCCRN) Univ of Utah Yes NICHD
CPCCRN 041: "Pediatric Intensive Care Quality of CPR (PICqCPR)" Univ of Utah Yes NICHD
CPCCRN 047: Biomarker Phenotyping of Pediatric Sepsis and Multiple Organ Failure (PHENOMS) Univ of Utah Yes NICHD
CPCCRN 053: Life After Pediatric Sepsis Evaluation (LAPSE) Univ of Utah Yes NICHD
CPCCRN 054: Inhaled Nitric Oxide Use in Pediatric Intensive Care (Nitric Oxide) Univ of Utah Yes NICHD
CPCCRN 059: Pediatric ECMO and Cefepime (PEACE) Univ of Utah Yes NICHD
CPCCRN 062: Sepsis-induced red blood cell dysfuction (SiRD) (SiRD Study) Univ of Utah Yes NICHD
CPCCRN 064: GM-CSF for Immunomodulation Following Trauma (GIFT)-1 Study Univ of Utah Yes NICHD
CPCCRN 065: Microbiome, Virome and Host Responses Preceding Ventilator-Associated Pneumonia (VAP) Univ of Utah Yes NICHD
CPCCRN 066: Informing the Research Agenda for Pediatric Intensive Care Units (IRA) Univ of Utah Yes NICHD
CPCCRN 068: Improving Outcomes from Pediatric Cardiac Arrest (ICU-RESUS) Univ of Utah Yes NICHD
CPCCRN 075: Parent-Provider Alliance in Pediatric Intensive Care (PPA) Univ of Utah Yes NICHD
CPCCRN 076: Assessment of Health-Related Quality of Life and Functional Outcomes after Pediatric Trauma (TOUCH) Univ of Utah Yes NICHD
CPCCRN 077: Sepsis-Induced Red Cell Dysfunction (SiRD Study) Univ of Utah Yes NICHD
CPCCRN 079: Acute Respiratory Distress Syndrome (ARDS) Univ of Utah Yes NICHD
CPCCRN 080: CPCCRN Central Biorepository Univ of Utah Yes NICHD
CPCCRN 082: Core Outcomes Set (COS) for Pediatric Critical Care Medicine (PCCM) Research (PICU Core Outcomes) Univ of Utah Yes NICHD
Creation and maintenance of integrated biorepository databases (IBD) to support research usage of biorepository samples. Pennington Biomed Yes LaCaTS
Cystic Fibrosis Foundation Patient Registry - PortCFv.2 Tulane Univ Yes Other
Dexmedetomidine Opioid Sparing Effect in Mechanically Ventilated Children (DOSE Trial) Vanderbilt Univ Med Ctr Yes NIH
ECHO: eaRly dAta subMission Protocol - RAMP Vanderbilt Univ Med Ctr Yes NIH
Efficacy of a Gluten-free Diet in Difficult-to-Manage Nephrotic Syndrome: Utility of Plasma Zonulin Levels as a Predictive Biomarker Vanderbilt Univ Med Ctr Yes NIH
EFIC CIRB: Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children (TIC-TOC): A Pilot and Feasibility Study Univ of Utah Yes NICHD
Evaluation of Valproic Acid (VPA) as Adjunctive Therapy for Liver Transplant Patients with Moderate to Severe Hemorrhage at Risk of Ischemia Reperfusion (I/R) Injury (VPA-202) Vanderbilt Univ Med Ctr No Other
Evaluation of Valproic Acid (VPA) as Adjunctive Therapy for Trauma Patients with Moderate to Severe Hemorrhage at Risk of Ischemia Reperfusion (I/R) Injury (VPA-201) Vanderbilt Univ Med Ctr No Other
Fit to Learn: A Digital Intervention to Improve Fundamental Motor Skills in Young Children Pennington Biomed Yes NIH
FLOWER-BED: Workflow for EHR-embedded clinical trials Vanderbilt Univ Med Ctr Yes NHLBI
GENETIC AND ENVIRONMENTAL INFLUENCES ON RECOVERY OF SEVERE PEDIATRIC BRAIN INJURY Cincinnati Children's Yes NINDS
Genomic Medicine for III Neonates and Infants [GEMINI] Johns Hopkins Univ SOM Yes NIH
GP IDeA CTR Alzheimer's Disease Registry Univ Nebraska Med Ctr No NIA
Greenlight Plus Study: A Randomized Study of Approaches to Early Childhood Obesity Prevention Vanderbilt Univ Med Ctr Yes PCORI
High Dose vs. Standard Dose Flu Vaccine in Adult Stem Cell Transplant Recipients Vanderbilt Univ Med Ctr Yes NIH
Impact of a CMS Reimbursement Policy Supporting Care Coordination in Louisiana Tulane Univ Yes PCORI
Interventions Against Insulin Resistance in Pulmonary Arterial Hypertension Vanderbilt Univ Med Ctr Yes NIH
Investigating Social Competence in Youth with Autism: A Multisite RCT Vanderbilt Univ Med Ctr Yes Investigator
Investigation of the Efficacy of Antimycobacterial Therapy on Pulmonary Sarcoidosis Phase II Randomized, Double-blind, Placebo-controlled Trial (CLEAR II) Vanderbilt Univ Med Ctr Yes NIH
LCH-IV: International Collaborative Treatment Protocol For Children and Adolescents with Langerhans Cell Histiocytosis St. Jude Children's Yes Other
Longitudinal Early-onset Alzheimer's Disease Study (LEADS) Indiana Univ Yes NIH
Measuring OutcomeS of Activity in Intensive Care (MOSAIC) Vanderbilt Univ Med Ctr No NIA
Molecular Transducers of Physical Activity Consortium (MoTrPAC) Johns Hopkins Univ SOM No NIH
Multi Site Development of a multimodal biomarker platform for predictive risk stratification of cardiac disease in Duchenne muscular dystrophy Vanderbilt Univ Med Ctr Yes unknown
Multi Site Health Disparities and GIS Analysis Project Vanderbilt Univ Med Ctr Yes NIH
Nashville Longitudinal Study of Youth Safety and Wellbeing Vanderbilt Univ Med Ctr Yes Investigator
National Registry for Childhood Interstitial and Diffuse Lung Diseases Vanderbilt Univ Med Ctr Yes Investigator
NEUROETHICS OF ADBS SYSTEMS TARGETING NEUROPSYCHIATRIC AND MOVEMENT DISORDERS Baylor College Med Yes NIMH
Novel screening strategy for systemic sclerosis-associated pulmonary hypertension incorporating endothelial biomarkers. LSU HSC New Orleans Yes Other
Obesity, Health Disparities and Cancer Risk in Louisiana: Specific Aim 1 Pennington Biomed Yes LaCaTS
Obesity-Related Cancer Risk in Mississippi, Alabama, and Louisiana Pennington Biomed Yes LaCaTS
Operative versus Non-Operative Treatment for Atraumatic Rotator Cuff Tears: A Multicenter Randomized Controlled Pragmatic Trial Vanderbilt Univ Med Ctr Yes PCORI
Painted Playgrounds: A scalable approach to increasing physical activity and motor skills in Louisiana preschool aged children. Aim 2: Assessments Pennington Biomed Yes Other
Pathologic Fractures Associated with Osteomyelitis in the Pediatric Population Vanderbilt Univ Med Ctr Yes NIH
Patient and Caregiver Preferences for Treatment of Hemophilia A Tulane Univ Yes Other
Patient Perspective in Living with Manifestations of Connective Tissue Diseases Tulane Univ Yes unknown
PECARN 041: Implementation of evidence based care for the acute treatment of sickle cell disease pain Univ of Utah Yes NHLBI
PECARN 043: The Effect of Emergency Department and After-Emergency Department Analgesic Treatment on Pediatric Long Bone Fracture Outcomes (After ED Fracture Outcomes) Univ of Utah Yes NICHD
PECARN: Development and Testing of a Pediatric Cervical Spine Injury Risk Assessment Tool (C-Spine) Univ of Utah Yes NICHD
PECARN: ED-Initiated School-based Asthma Medication Supervision (ED-SAMS) Univ of Utah Yes NHLBI
PECARN: Improving the Detection of STIs in the Pediatric Emergency Department: A Pragmatic Trial Univ of Utah Yes NICHD
PediAtric ReseArch of Drugs, Immunoparalysis and Genetics during MODS (PARADIGM) Nationwide Children's No NICHD
PHACS PH204 (Ver 1.0) 01/17/2018 A Re-Examination of Oral Health among Participants in PHACS Adolescent Master Protocol (AMP - PH200) and Adolescent Master Protocol for Participants 18 Years of Age and Older (AMP Up - PH300) Tulane Univ Yes NIDCR
Physical Activity and Screen-Time Regulations in Childcare Centers: Influence on Young Children's Health Behaviors (Pause & Play) - Aim 2 Pennington Biomed Yes NIH
Pilot validation of an app to estimate and manage portion size: The PortionSize Smartphone App Pennington Biomed Yes Investigator
Pointer Wake Forest Univ Hlth Sci Yes Other
PPHNet Biospecimen Laborator Depot (PPHNet-BOLD) Vanderbilt Univ Med Ctr Yes NHLBI
Prazosin for Disruptive Agitation in Alzheimer's Disease (AD) (PEACE-AD) Johns Hopkins Univ SOM Yes NIA
Precision Interventions for Severe and/or Exacerbation-Prone Asthma (PrecISE) Network Vanderbilt Univ Med Ctr No NHLBI
Precision Medicine & Health Disparities Collaborative- Perspectives on Precision Medicine Vanderbilt Univ Med Ctr Yes NCMHD
Preventing cardiovascular collapse with Administration of fluid Resuscitation during Induction and Intubation (PREPARE II) Vanderbilt Univ Med Ctr Yes unknown
Prospective randomized clinical trial comparing outcomes of secondary intention wound care methods Lahey Clinic No Other
Prospective Tissue and Clinical Database for Ovarian Cancer Studies Vanderbilt Univ Med Ctr Yes NIH
Randomized Controlled Trial of Valganciclovir for Asymptomatic Cytomegalovirus Infected Hearing Impaired Infants (ValEAR Trial) Univ of Utah Yes NIDCD
Renal Pathology Vanderbilt Univ Med Ctr Yes Investigator
Research Into Visual Endpoints and RB Health Outcomes After Treatment (RIVERBOAT) Vanderbilt Univ Med Ctr Yes NIH
Resistance Exercise and Low-Intensity Physical Activity Breaks in Sedentary Time to Improve Skeletal Muscle and Cardiometabolic Health in Older Adults-REALPA Breaks in Sedentary Time Pilot Study Pennington Biomed Yes NIH
Risk Stratification and Decision Support to Improve Care and Outcomes in Children with Pneumonia Vanderbilt Univ Med Ctr Yes NIH
Single Dose Versus 5-Day Dosing of an Aromatase Inhibitor for Ovulation Induction Woman's Hosp Fdn No Investigator
sIRB (VUMC): Bougie or Stylet In Patients Undergoing Intubation Emergently (BOUGIE Trial) Vanderbilt Univ Med Ctr Yes Other
sIRB (VUMC): IFOPA Biobank of Tissues from Patients with Fibrodysplasia Ossificans Progressiva and Control Subjects Vanderbilt Univ Med Ctr Yes Other
sIRB (VUMC): Improving CarE for Community Acquired Pneumonia (ICE CAP) Vanderbilt Univ Med Ctr Yes NIAID
sIRB (VUMC): Observational Study of Expected ARF Recovery (OSEAR) Vanderbilt Univ Med Ctr Yes NIH
SIRB (VUMC): Primary Ciliary Dyskinesia (PCD) Foundation Clinical Registry Vanderbilt Univ Med Ctr Yes Other
Steroids to reduce systemic inflammation after infant heart surgery (STRESS) study Vanderbilt Univ Med Ctr Yes NIH
Strengthening Translational Research and Diverse Enrollment (STRIDE) Univ Mass Med Sch Yes NIH
Sudden Death in the Young Registry -- Family Sub-Study Vanderbilt Univ Med Ctr Yes NIH
Systemic treatment of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Pilot Study in Advance of a Phase III Clinical Trial Vanderbilt Univ Med Ctr Yes NIH
Telmisartan Plus Exercise to Improve Functioning in PAD: The TELEX Trial Ochsner Clinic Fdn No NIH
Test Project - 20180907 TS1 No NEI
Test Project - 20180907_2 TS1 No NEI
Test Project - Before Site Amendment Push TS1 Yes Investigator
Test Project -After Amendment TS1 Yes CSR
The Current and Potential Effects of Cancer Screening on Health Outcomes Pennington Biomed Yes LaCaTS
The Effect of Antibiotics on Latency in Previable Prelabor Rupture of Membranes Between 18 0/7 and 22 6/7 Weeks Gestational Age Woman's Hosp Fdn Yes Investigator
The Effect of Higher Protein Dosing in Critically Ill Patients: A Multicenter Registry-based Randomized Trial The EFFORT Trial Vanderbilt Univ Med Ctr Yes Investigator
The Exercise And Colon Cancer Treatment (EXACT) Trial Pennington Biomed Yes NIH
The Influence of Time-to-Diagnosis on Time-To-Treatment for STEMI Patients Vanderbilt Univ Med Ctr Yes NIH
The Peer-based Retention of People who Use Drugs in Rural Research (PROUD-R2) Univ of Utah Yes NIH
TIN CIRB (VUMC): Comparing primary care clinician-focused versus team-based implementation of advance care planning (META LARC) Vanderbilt Univ Med Ctr Yes PCORI
TIN CIRB (VUMC): The Impact of Low Flow Nocturnal Oxygen Therapy on Hospital Admissions and Mortality in Patients with Heart Failure and Central Sleep Apnea (LOFT-HF) Vanderbilt Univ Med Ctr Yes NHLBI
To Sleep or To Study? An inquiry into sleep disorders among allied health students LSUHSC at Shreveport Yes unknown
TRaditional versus Early Aggressive Therapy for Multiple Sclerosis (TREAT-MS) Trial Johns Hopkins Univ SOM Yes PCORI
Unexpected Clinical Events: Impact on Patient Safety: Part 2 Vanderbilt Univ Med Ctr Yes NICHD
Using Natural Language Processing to Identify LGBTI Patients in the VUMC EMR and determine how LGBTI status affects diagnosis, treatment, and health outcomes Vanderbilt Univ Med Ctr Yes Investigator
Validation of an Objective Instrument to Measure Hot Flashes during Menopause Pennington Biomed Yes NIH
Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) Trial. Johns Hopkins Univ SOM Yes Other
Zoster Eye Disease Study (ZEDS): A multi-center, randomized, double-masked, placebo-controlled clinical trial of suppressive valacyclovir for one year in immunocompetent study participants with a history of dendriform epithelial keratitis, stromal keratitis, endothelial keratitis, and/or iritis due to Herpes Zoster Ophthalmicus (HZO) in the year prior to enrollment Vanderbilt Univ Med Ctr Yes NEI

Leave a Reply