Category Archives: FRL

Bug Fixes – March 13, 2024

Enhanced: Modified UI when indicating a study-wide amendment has a protocol change.
Fixed: Amendment # field removed from initial and continuing review approval dialog.
Fixed: Relying site notification about updated approval now displaying table of changes.
Fixed: Bug breaking ability to create a new site amendment.
Fixed: Reviewing IRBs and/or Study Managers cannot Request Agreements if IREx Setup and Primary Study Team Contacts incomplete, to prevent missing information on the notification.

New Feature: Reviewing IRBs can now request Relying Sites update their Local Considerations throughout the life of a study

In the IREx Study Setup, Reviewing IRBs/sIRBs can choose to have IREx notify relying sites when a study-wide amendment is posted, and request sites update their local considerations in IREx if necessitated by the study changes. If sIRBs choose this option, they can also opt to choose a number of days sites have to submit their updates in IREx. This feature is only available on studies in which the sIRB is collecting local considerations in IREx.

Updated Feature: Modified amendment approval email notification

The amendment approval notification sent to relying sites has been modified for studies capturing local consideration updates for the life of a study. The email subject changed from, “IREx: New IRB Approval For Your Site.” to “ATTN: Approved changes may require local review.” A new Amendment Content section outlines the type of changes and a link on how to edit the surveys is also included.

Updated Feature: Study Reports now shows which studies are capturing Local Consideration updates

The Overall Study and Participating Site Report has a new column, ‘isCapturingLocalContextUpdates’ to indicate which studies in IREx are capturing Local Considerations updates for the life of a study. Reviewing IRBs can download the Overall Study Report (CSV) and the Participating Site Report (CSV) from their Reviewing Site’s Studies Dashboard from the Export menu.

Updated Feature: Relying sites can now edit the HRP and PI Survey after receiving Initial Approval

Prior to February 2024, the HRP and PI Survey was not editable after a relying site received initial approval in IREx. Now, the Relying HRPP can edit both the HRP and PI Survey and the relying site Study Team Members and PI can edit the PI Survey after initial approval, as needed. Editing the surveys in IREx helps align any site changes. IREx will notify the Reviewing IRB and Study Managers when changes to the surveys are made.

Updated Feature: Relabeled Getting Started Checklist

The Getting Started Checklist has been relabeled to “Checklist.” IREx removed the “Getting Started” label since the Checklist can be used after a site receives initial approval (e.g., edit local considerations and adding study contacts). Reviewing IRBs and Study Managers also continue to use the Checklist for ongoing approvals for the life of the study.

Updated Feature: “Not Approved” status now hidden on the Status Summary tab until site completes all steps

On the Status Summary Tab, the “Not Approved” status is now hidden until the site completes all steps needed for sIRB review. These steps include the completion of agreements, reliance decision, and local considerations if applicable for the study. This is to ensure a site has completed all necessary steps before site approval is uploaded.