What is the IRB Reliance Exchange (IREx)?

IREx is a freely available web-based portal that supports single IRB (sIRB) documentation and communication for multi-center clinical trials, such as:

Using IREx: Who and how?

Single IRBs
use IREx to centrally capture information from site HRPPs/IRBs and study teams that cannot access their system
Participating Site HRPPs/IRBs
use IREx to document reliance and local reviews for the sIRB.
Coordinating Centers
 use IREx to track site progress as they complete the steps to sIRB approval.

Participating Site Study teams
use IREx to document information for the sIRB and to retrieve approvals from the sIRB

Why Use IREx?